| Date / Day | Opponent / Location | Time (CT) / TV | |
| 09/01/18 (Saturday) |
 |
Washington MB Stadium Atlanta, GA |
W, 21-16 |
| 09/08/18 (Saturday) |
 |
Alabama State Jordan-Hare Auburn, AL |
W, 63-9 |
| 09/15/18 (Saturday) |
 |
LSU Jordan-Hare Auburn, AL |
L, 21-22 |
| 09/22/18 (Saturday) |
 |
Arkansas Jordan-Hare Auburn, AL |
W, 34-3 |
| 09/29/18 (Saturday) |
 |
Southern Miss Jordan-Hare Auburn, AL |
W, 24-13 |
| 10/06/18 (Saturday) |
 |
@ Miss. State Davis Wade Stadium Starkville, MS |
L, 9-23 |
| 10/13/18 (Saturday) |
 |
Tennessee Jordan-Hare Auburn, AL |
L, 24-30 |
| 10/20/18 (Saturday) |
 |
at Ole Miss Vaught-Hemingway Stadium Oxford, MS |
W, 31-16 |
| 10/27/18 (Saturday) |
— | OPEN | |
| 11/03/18 (Saturday) |
 |
Texas A&M Jordan-Hare Auburn, AL |
W, 28-24 |
| 11/10/18 (Saturday) |
 |
Georgia Sanford Stadium Athens, GA |
L, 10-17 |
| 11/17/18 (Saturday) |
 |
Liberty Jordan-Hare Auburn, AL |
W, 53-0 |
| 11/24/18 (Saturday) |
 |
Alabama Bryant-Denny Stadium Tuscaloosa, AL |
L, 21-52 |
| 12/28/18 (Friday) |
 |
Music City Bowl Auburn vs. Purdue Nashville, TN |
W, 63-14 |
